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创源大讲堂系列讲座
作者:魏久林     日期:2016-09-20     点击数:255  

讲座一:Liquid Crystals for Imaging and Sensing Applications

         液晶在显示和传感领域的应用

主 讲 人:Prof. Jiyu Fang,Department of Materials Science and Engineering, University of Central Florida, Orlando, FL

内容简介:Liquid crystals (LCs) are a sensitive material with long-range orientational order. The orientation of LCs is sensitive to the change of the surface which they are in contact with. This surface-induced local order can be amplified over several tens of micrometers in LC bulk due to the long-range interaction of LCs. In this talk, I will discuss the application of the optical amplification of LCs in imaging the defects of lipid membranes and sensing the biomarker of liver disease.

主讲人简介:Jiyu Fang received a BS in Physics from Nanjing Normal University in 1983, a MS in Physics from Chinese Academy of Science in 1989, and a PH.D in Biomedical Engineering from Southeast University in 1989. After two postdoctoral stints at Iowa State University and University of California at Los Angeles, he joined US Naval Research Laboratory as a research scientist in 1997. Currently, he is a Professor in the Department of Materials Science and Engineering at the University of Central Florida (UCF). Dr. Fang has co-authored 110 peer-reviewed publications. He received 2015-2016 and 2010-2011 UCF Research Incentive Award and 2009-2010 UCF Distinguished Research Award. Currently, he serves as Editor-in-Chief of Journal of Materials Science and Chemical Engineering.

 

讲座二:Selected fluid mechanics topics in printing

         基于液滴打印的流体力学问题

主 讲 人:Prof. Weiwei Deng

Department of Mechanical Engineering, Virginia Tech, Blacksburg, VA

内容简介:Rapid progress has been made in advanced manufacturing and 3D printing. Liquid droplet based printing is one of the promising techniques. To ensure the quality and resolution of the printed parts, the droplet size needs to be monodispersed with controllable size from sub-micrometer to a few micrometers. The monodispersed droplets are typically generated by breakup of liquid jets. The breakup of liquid jets is ubiquitous with rich underpinning physics and widespread applications. The natural breakup of liquid jets originates from small ambient perturbations, which can grow exponentially until the amplitude as large as the jet radius is reached. For unelectrified jets, only the axisymmetric perturbation is possibly unstable, and this mode is referred as varicose instability. For electrified jets, the presence of surface charge enables additional unstable modes, among which the most common one is the whipping instability that bends and stretches the charged jet. In the first part of this talk, I will report the interesting outcomes of breakup of electrified jets that undergo both varicose and whipping instabilities. The co-development of transverse and axisymmetric perturbations leads to remarkable jet breakup behavior attributable to initial perturbation magnitude, perturbation wavenumbers, and jet surface charge levels. We will also discuss the gas entrapment in liquid droplet impact on solid substrate. Such gas entrapment may form pin-holes and defects of printed parts. We present possible solutions in avoiding gas entrapment and eliminating pin-holes.

主讲人简介:Dr. Weiwei Deng is an Associate Professor in the Department of Mechanical Engineering at Virginia Tech. Prior to joining Virginia Tech, he has been an Assistant Professor in the Mechanical and Aerospace Engineering at the University of Central Florida (UCF). He received his Ph.D. in Mechanical Engineering from Yale University in 2008 and B.S. from Tsinghua University in China. Dr. Deng’s general research interest is the fluid dynamics of low-dimensional liquid subjects such as droplets, jets, and films. He is also interested in additive manufacturing with the focus on using single or multiplexed electrospray to process advanced energy materials. His group’s work has been featured as the cover article of Physical Review Letters. Dr. Deng is the National Science Foundation CAREER Award recipient in 2015.


讲座三:Spectroscopic Study of Protein Folding Dynamics

         蛋白质折叠动力学的光谱研究

主 讲 人:Prof. Feng Gai,Department of Chemistry, University of Pennsylvania, Philadelphia, PA 19104

内容简介:The stability of a protein can be easily determined. However, it is much more difficult to assess its folding dynamics and mechanism, especially the fine features of the underlying folding free energy landscape.  In this talk, we will discuss several experimental strategies that could be useful to help uncover dynamic and mechanistic information that is inaccessible via conventional folding kinetic measurements.

主讲人简介:Dr. Feng Gai received a BS in Chemistry in 1983 and a MS in Physical Chemistry in 1986, both from Peking University. He obtained a PhD in Physical Chemistry from Iowa State University in 1994. After two postdoctoral stints at Harvard University and Los Alamos National Laboratory, he joined the faculty at the University of Pennsylvania as an Assistant Professor in 1999. Currently, he holds the appointment of Edmund J. and Louise W. Kahn Term Professor of Chemistry and also directs the Ultrafast Optical Processes Laboratory at Penn. Dr. Gai has co-authored over 120 peer-reviewed publications and has delivered more than 130 invited talks at conferences and departmental seminars. His scholarly work at Penn has been recognized thorough several awards and distinctions, including a Research Innovation Award from the Research Corporation (2000), the CAREER Award from the National Science Foundation (2001), election to Fellow of the American Physical Society (2011) and the American Association for the Advancement of Science (2012), and an ACS Philadelphia Section Award (2014).


讲座四:Repair of sun-damaged DNA by enzymes

         太阳光致DNA损伤的酶修复方法

主 讲 人: Prof. Dongping Zhong

Department of Physics, Ohio State University, Columbus, Ohio

内容简介:UV radiation can damage DNA and such lesion may eventually lead to skin cancer. Photolyase, a photo-repair machine in nature, can revert such damage with high efficiency. Here, by integrating femtosecond spectroscopy and molecular biology, we have completely mapped out the entire repair evolution at the most fundamental level with unprecedented detail and thus reveal the complete repair photocycle.  A unified electron-transfer mechanism was elucidated for all photolyases and the critical role of the unique folded cofactor structure was determined. Such results provide the basic knowledge for potential biomedical applications of curing skin cancer.

主讲人简介:Dongping Zhong received his B.S. in laser physics from Huazhong University of Science and Technology in China and his Ph.D. in Chemical Physics from California Institute of Technology under Ahmed Zewail (1999 Nobel Laureate in Chemistry). For his Ph.D. work, Dr. Zhong received the Herbert Newby McCoy Award and the Milton and Francis Clauser Doctoral Prize from Caltech. He continued his postdoctoral research at Caltech with focus on protein dynamics. In 2002, he joined The Ohio State University as an Assistant Professor and currently he is Robert Smith Professor of Physics and Professor of Chemistry and Biochemistry. He is the Packard Fellow, Sloan Fellow, Camille Dreyfus Teacher-Scholar, Guggenheim Fellow, APS Fellow, AAAS Fellow, as well as the recipient of the NSF CAREER Award and the OCPA Outstanding Young Researcher Award. He is the committee member in the International July of Physical Science, The L’Oreal-UNESCO awards for Women in Science. His research interests integrate laser spectroscopy and molecular biology to study biomolecular interactions and dynamics, recently DAN-damage repair through strong collaboration with Aziz Sancar (2015 Nobel Laureate in Chemistry).


讲座五:Application of magnetic resonance (MR) imaging and spectroscopy in precision radiation therapy and patient outcome evaluation

                                                             磁共振成像和磁共振波普在精准放疗和定量分析治疗效果上的应用

主 讲 人:Yuenan (Nancy) Wang, PhD, DABR

Department of Radiation Oncology, University of Virginia, Charlottesville, Virginia 22908

内容简介:More than 50% of all cancer patients receive radiation therapy either for cure or for palliative purposes during their course of illness. The ionizing radiation can induce effective tumor kills; however, it can also damage the surrounding normal tissue. As a non-invasive and non-ionizing imaging method with superior soft tissue contrast, MRI and MRS are safe and effective to evaluate the tumor response and tissue toxicity, which makes MRI/MRS a suitable functional imaging modality for quantitatively analyzing treatment outcomes. In addition, MRI and MRS can also facilitate precise and accurate radiotherapy due to their flexible contrast mechanisms in soft tissue. More examples will be given about the clinical applications of MRI/MRS in image-guided radiotherapy (IGRT) and tumor response analysis.

主讲人简介:Dr. Wang joined the Department of Radiation Oncology as a member of the Clinical Physics faculty in 2015. She earned her Ph.D. in Engineering and Applied Science (ENAS) at Yale University in 2009 and has been board certified by American Board of Radiology (ABR).  Prior to joining UVA, she worked as a lead reviewer in Center for Devices and Radiological Health (CDRH) at U.S. Food and Drug Administration (FDA). In her current role, she provides clinical coverage for the TomoTherapy Unit, TrueBeam and Trilogy linear accelerators. Dr. Wang also facilitates treatment planning and image registration. Her research interest is focused on tumor metabolism study using magnetic resonance imaging (MRI) or magnetic resonance spectroscopy (MRS), bioprinted 3D tumor models for quantitative radiation therapy investigation, image guided radiotherapy (IGRT), and intensity modulated radiotherapy (IMRT).