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“创源”大讲堂研究生讲座:Cross-Coupling Reactions of Organoboranes: An Easy Way for Carbon-Carbon

作者:李雪     审核:    日期:2018年05月10日 00:00   点击数:  

报告题目Cross-Coupling Reactions of Organoboranes: An Easy Way for Carbon-Carbon

Bonding 

Akira SUZUKI2010年诺贝尔化学奖获得者)

报告时间20180515日(星期二)下午14:00

报告地点:西南交通大学犀浦校区X9305

人:侯进副教授

 

讲座内容简介: The palladium-catalyzed cross-coupling reaction between different types of organoboron compounds and various organic halides or triflates in the presence of base provides a powerful and general methodology for the formation of carbon-carbon bonds. The (sp3)C-B compounds (alkylboron compounds) and (sp2)C-B compounds (such as aryl- and 1-alkenylboron derivatives) readily cross-couple with organic electrophiles to give coupled products selectively in high yields. Recently, the (sp)C-B compounds (1-alkynylboron derivatives) have been also observed to react with organic electrophiles to produce expected cross-coupled products. Such coupling reactions offer several advantages:        

(1) ready availability of reactants; (2) mild reaction conditions; (3) water stability; (4) easy use of the reaction both in aqueous and heterogeneous conditions; (5) toleration of a broad range of functional groups; (6) high regio- and stereoselectivity of the reaction; (7) insignificant effect of steric hindrance; (8) use of a small amount of catalysts; (9) application in one-pot synthesis; (10)  nontoxic reaction; (11) easy separation of inorganic boron compound; (12) green chemistry. 

These coupling reactions have been actively utilized not only in academic laboratories but also in industrial processes including pharmaceutical and agrochemical industries, and liquid crystal and OELD production. 

In this lecture, the overview of the coupling reaction will be discussed to understand the whole.

 

IMG_256告人简介:铃木章(Akira SUZUKI),毕业于北海道大学,是日本化学家、北海道大学荣誉教授和铃木反应的发现者。因在有机合成中的钯催化交叉偶联反应方面做出贡献,时任北海道大学教授的铃木章与理查德·赫克根岸英一共同获得了2010诺贝尔化学奖

1954 北海道大学理学部化学科毕业。1959 北海道大学院理学研究科化学专业博士。1961 北海道大学工学部合成化学工学科 助理教授。1963 美国普渡大学 博士研究员(H.C.Brown教授)。1973 北海道大学工学部应用化学科 教授。1994 冈山理科大学 教授。1995 仓敷艺术科学大学 教授。2001 美国普渡大学 特邀教授。2002 台湾中央科学院和台湾大学 特邀教授。1986 Weissberger-Williams Lectureship Award1987 韩国化学会功劳奖。1989 日本化学会奖。1995 DowElanco Lectureship Award2000 The H. C. Brown Lecture Award2003 有机合成化学协会特别奖。

2004 日本学士院奖(对钯催化的新有机合成反应的研究)。2010 诺贝尔化学奖(对有机合成中钯催化偶联反应的研究)。

 

欢迎广大师生积极参听!

主办:研究生院

承办:信息科学与技术学院

 

“创源”大讲堂研究生讲座:Cross-Coupling Reactions of Organoboranes: An Easy Way for Carbon-Carbon

2018年05月10日 00:00 510次浏览

报告题目Cross-Coupling Reactions of Organoboranes: An Easy Way for Carbon-Carbon

Bonding 

Akira SUZUKI2010年诺贝尔化学奖获得者)

报告时间20180515日(星期二)下午14:00

报告地点:西南交通大学犀浦校区X9305

人:侯进副教授

 

讲座内容简介: The palladium-catalyzed cross-coupling reaction between different types of organoboron compounds and various organic halides or triflates in the presence of base provides a powerful and general methodology for the formation of carbon-carbon bonds. The (sp3)C-B compounds (alkylboron compounds) and (sp2)C-B compounds (such as aryl- and 1-alkenylboron derivatives) readily cross-couple with organic electrophiles to give coupled products selectively in high yields. Recently, the (sp)C-B compounds (1-alkynylboron derivatives) have been also observed to react with organic electrophiles to produce expected cross-coupled products. Such coupling reactions offer several advantages:        

(1) ready availability of reactants; (2) mild reaction conditions; (3) water stability; (4) easy use of the reaction both in aqueous and heterogeneous conditions; (5) toleration of a broad range of functional groups; (6) high regio- and stereoselectivity of the reaction; (7) insignificant effect of steric hindrance; (8) use of a small amount of catalysts; (9) application in one-pot synthesis; (10)  nontoxic reaction; (11) easy separation of inorganic boron compound; (12) green chemistry. 

These coupling reactions have been actively utilized not only in academic laboratories but also in industrial processes including pharmaceutical and agrochemical industries, and liquid crystal and OELD production. 

In this lecture, the overview of the coupling reaction will be discussed to understand the whole.

 

IMG_256告人简介:铃木章(Akira SUZUKI),毕业于北海道大学,是日本化学家、北海道大学荣誉教授和铃木反应的发现者。因在有机合成中的钯催化交叉偶联反应方面做出贡献,时任北海道大学教授的铃木章与理查德·赫克根岸英一共同获得了2010诺贝尔化学奖

1954 北海道大学理学部化学科毕业。1959 北海道大学院理学研究科化学专业博士。1961 北海道大学工学部合成化学工学科 助理教授。1963 美国普渡大学 博士研究员(H.C.Brown教授)。1973 北海道大学工学部应用化学科 教授。1994 冈山理科大学 教授。1995 仓敷艺术科学大学 教授。2001 美国普渡大学 特邀教授。2002 台湾中央科学院和台湾大学 特邀教授。1986 Weissberger-Williams Lectureship Award1987 韩国化学会功劳奖。1989 日本化学会奖。1995 DowElanco Lectureship Award2000 The H. C. Brown Lecture Award2003 有机合成化学协会特别奖。

2004 日本学士院奖(对钯催化的新有机合成反应的研究)。2010 诺贝尔化学奖(对有机合成中钯催化偶联反应的研究)。

 

欢迎广大师生积极参听!

主办:研究生院

承办:信息科学与技术学院